The fastest intelligent recruitment engine.
Meet critical timelines.
Break the clinical trial bottleneck with TrialWire ® Unmatched speed, precision and transparency for biotechs and CROs, powered by agentic Al, advanced algorithms and the security of Salesforce Health Cloud. HIPAA & GDPR compliant.
Recognized Leader
Award-winning solution
The most awarded Platform
Recognized Leader
Award-winning solution
The most awarded Platform
Recognized Leader
Award-winning solution
The most awarded Platform
Process
Process
Process
From Activation to Referrals, in Minutes
Find | Screen | Engage
1.
People Finder Algorithms
Smart algorithms find people actively seeking health solutions online matched to your trial’s therapeutic area
1.
People Finder Algorithms
Smart algorithms find people actively seeking health solutions online matched to your trial’s therapeutic area
1.
People Finder Algorithms
Smart algorithms find people actively seeking health solutions online matched to your trial’s therapeutic area
2.

AI-Match Screener
AI-Match screener evaluates eligibility against your protocol criteria. Learns from referral and enrollment activity.
2.

AI-Match Screener
AI-Match screener evaluates eligibility against your protocol criteria. Learns from referral and enrollment activity.
2.

AI-Match Screener
AI-Match screener evaluates eligibility against your protocol criteria. Learns from referral and enrollment activity.
3.
Engage & Enroll
Data portal enhanced with smart communications sytem ensures sites and referrals rapidly connect to progress to enrollment.
3.
Engage & Enroll
Data portal enhanced with smart communications sytem ensures sites and referrals rapidly connect to progress to enrollment.
3.
Engage & Enroll
Data portal enhanced with smart communications sytem ensures sites and referrals rapidly connect to progress to enrollment.
Built for Success
Built for Success
Built for Success
Compliance & Unmatched Speed
Supporting Sites and Sponsors
Built for Scale
Designed for multi-site, multi-study trials across regions.
Built for Scale
Designed for multi-site, multi-study trials across regions.
Built for Scale
Designed for multi-site, multi-study trials across regions.




Enterprise-grade Security
HIPAA and GDPR compliant on Salesforce Health Cloud.



Enterprise-grade Security
HIPAA and GDPR compliant on Salesforce Health Cloud.



Enterprise-grade Security
HIPAA and GDPR compliant on Salesforce Health Cloud.
Real-time Data Portal
Sponsors and CROs get real-time progress data. Track referrals, eligibility, and enrollment live across every site and study.
Real-time Data Portal
Sponsors and CROs get real-time progress data. Track referrals, eligibility, and enrollment live across every site and study.
Real-time Data Portal
Sponsors and CROs get real-time progress data. Track referrals, eligibility, and enrollment live across every site and study.
Advanced Communications
Algorithms, AI-Match, Unified Communications Stystem and real time data transparencey across all sites and studies.
Advanced Communications
Algorithms, AI-Match, Unified Communications Stystem and real time data transparencey across all sites and studies.
Advanced Communications
Algorithms, AI-Match, Unified Communications Stystem and real time data transparencey across all sites and studies.
Rapid Referral Engagement
Strong engagement with referrals support enrollment and retention.
Rapid Referral Engagement
Strong engagement with referrals support enrollment and retention.
Rapid Referral Engagement
Strong engagement with referrals support enrollment and retention.
Features
Features
Features
Designed to Meet Critical Timelines
All the features you need
Unmatched Speed
Activate in 24 hours – No IRB or EC submission required
Unmatched Speed
Activate in 24 hours – No IRB or EC submission required
Unmatched Speed
Activate in 24 hours – No IRB or EC submission required
Unmatched Security
Powered by Salesforce Health Cloud with encrypted, privacy first architecture
Unmatched Security
Powered by Salesforce Health Cloud with encrypted, privacy first architecture
Unmatched Security
Powered by Salesforce Health Cloud with encrypted, privacy first architecture
HIPAA and GDPR Compliant
Ensuring patient data privacy, regulatory confidence and enterprise-grade security
HIPAA and GDPR Compliant
Ensuring patient data privacy, regulatory confidence and enterprise-grade security
HIPAA and GDPR Compliant
Ensuring patient data privacy, regulatory confidence and enterprise-grade security
Real-time Transparency
Live visibility across referrals, follow-up and site activity - plus downloadable reporting
Real-time Transparency
Live visibility across referrals, follow-up and site activity - plus downloadable reporting
Real-time Transparency
Live visibility across referrals, follow-up and site activity - plus downloadable reporting
Global Footprint
Designed to support regional and global studies across all phases of development
Global Footprint
Designed to support regional and global studies across all phases of development
Global Footprint
Designed to support regional and global studies across all phases of development
Outcome Based Pricing
Risk share model – pay for enrolled participants
Outcome Based Pricing
Risk share model – pay for enrolled participants
Outcome Based Pricing
Risk share model – pay for enrolled participants
Benefits
Benefits
Benefits
Why Sponsors Choose TrialWire
Here’s why teams choose us over traditional tools.
The TrialWire Solution
24 hour rapid activation
AI-driven screening
Real-time reporting
Advanced data portal for sites and sponsors
Unified communications for sites
Secure on Salesforce Health Cloud
The TrialWire Solution
24 hour rapid activation
AI-driven screening
Real-time reporting
Advanced data portal for sites and sponsors
Unified communications for sites
Secure on Salesforce Health Cloud
The TrialWire Solution
24 hour rapid activation
AI-driven screening
Real-time reporting
Advanced data portal for sites and sponsors
Unified communications for sites
Secure on Salesforce Health Cloud
Other Recruitment Companies
Months to launch
Manual forms
Delayed reports
Fragmented systems
Website and email security challenges
Other Recruitment Companies
Months to launch
Manual forms
Delayed reports
Fragmented systems
Website and email security challenges
Other Recruitment Companies
Months to launch
Manual forms
Delayed reports
Fragmented systems
Website and email security challenges
Proven Results. Measurable Impact.
85
%
Improvement in participant contact
20
x
Faster recruitment
98
%
Screening accuracy
12
AI & Algorithm tools
24/7
Recruitment
85
%
Improvement in participant contact
20
x
Faster recruitment
98
%
Screening accuracy
12
AI & Algorithm tools
24/7
Recruitment
85
%
Improvement in participant contact
20
x
Faster recruitment
98
%
Screening accuracy
12
AI & Algorithm tools
24/7
Recruitment
Rapid Start
Rapid Start
Rapid Start
Onboarding & Activation
Fast onboarding & instant reporting

Start in 24 Hours

People Finder Algorithms

AI-Match Screener

Site/Referral Contact

Enrolled

24 Hour Start

Built for Speed. Secure by default.
Contract executed, core protocol details shared and study configured on the platform in under 24 hours. No IRB/EC submission required so recruitment can begin immediately.
24 hrs
Start - No IRB/EC submission required
24 hrs
Site activation & onboarding

Start in 24 Hours

People Finder Algorithms

AI-Match Screener

Site/Referral Contact

Enrolled

24 Hour Start

Built for Speed. Secure by default.
Contract executed, core protocol details shared and study configured on the platform in under 24 hours. No IRB/EC submission required so recruitment can begin immediately.
24 hrs
Start - No IRB/EC submission required
24 hrs
Site activation & onboarding

Start in 24 Hours

People Finder Algorithms

AI-Match Screener

Site/Referral Contact

Enrolled

24 Hour Start

Built for Speed. Secure by default.
Contract executed, core protocol details shared and study configured on the platform in under 24 hours. No IRB/EC submission required so recruitment can begin immediately.
24 hrs
Start - No IRB/EC submission required
24 hrs
Site activation & onboarding
Clients
Clients
Clients
Trusted by Leading Biotechs and CROs
Clients stay with us through all their phases
Testimonials
Testimonials
Testimonials
What Our Clients Are Saying
Trusted by Sponsors and CROs

Biotech
Boston, USA
"Great news! We're on track to hit our enrollment goal and would like to pause the incoming referrals via TrialWire."
We let the system do it's job and were very pleased with the result. Support helped quickly to get our sites logged in.

Biotech
Bay Area, USA
"Thanks again we will be back for Phase 3 and will start with TrialWire rather than bring you on for trial rescue again.”
We needed patients across 7 sites urgently and they delivered - they literally started in under 24 hours awith great support.

Biotech
San Diego, USA
"Just wanting to let you know that the referrals are flowing in and we are very excited to see all the activity.”
We wanted to get patients in quickly at startup to support our sites. They really delivered so there were no delays.

Biotech
Boston, USA
"Great news! We're on track to hit our enrollment goal and would like to pause the incoming referrals via TrialWire."
We let the system do it's job and were very pleased with the result. Support helped quickly to get our sites logged in.

Biotech
Bay Area, USA
"Thanks again we will be back for Phase 3 and will start with TrialWire rather than bring you on for trial rescue again.”
We needed patients across 7 sites urgently and they delivered - they literally started in under 24 hours awith great support.

Biotech
San Diego, USA
"Just wanting to let you know that the referrals are flowing in and we are very excited to see all the activity.”
We wanted to get patients in quickly at startup to support our sites. They really delivered so there were no delays.

Biotech
Boston, USA
"Great news! We're on track to hit our enrollment goal and would like to pause the incoming referrals via TrialWire."
We let the system do it's job and were very pleased with the result. Support helped quickly to get our sites logged in.

Biotech
Bay Area, USA
"Thanks again we will be back for Phase 3 and will start with TrialWire rather than bring you on for trial rescue again.”
We needed patients across 7 sites urgently and they delivered - they literally started in under 24 hours awith great support.

Biotech
San Diego, USA
"Just wanting to let you know that the referrals are flowing in and we are very excited to see all the activity.”
We wanted to get patients in quickly at startup to support our sites. They really delivered so there were no delays.

Biotech
Boston, USA
"Great news! We're on track to hit our enrollment goal and would like to pause the incoming referrals via TrialWire."
We let the system do it's job and were very pleased with the result. Support helped quickly to get our sites logged in.

Biotech
Bay Area, USA
"Thanks again we will be back for Phase 3 and will start with TrialWire rather than bring you on for trial rescue again.”
We needed patients across 7 sites urgently and they delivered - they literally started in under 24 hours awith great support.

Biotech
San Diego, USA
"Just wanting to let you know that the referrals are flowing in and we are very excited to see all the activity.”
We wanted to get patients in quickly at startup to support our sites. They really delivered so there were no delays.

Biotech
Boston, USA
"Great news! We're on track to hit our enrollment goal and would like to pause the incoming referrals via TrialWire."
We let the system do it's job and were very pleased with the result. Support helped quickly to get our sites logged in.

Biotech
Bay Area, USA
"Thanks again we will be back for Phase 3 and will start with TrialWire rather than bring you on for trial rescue again.”
We needed patients across 7 sites urgently and they delivered - they literally started in under 24 hours awith great support.

Biotech
San Diego, USA
"Just wanting to let you know that the referrals are flowing in and we are very excited to see all the activity.”
We wanted to get patients in quickly at startup to support our sites. They really delivered so there were no delays.

Biotech
Boston, USA
"Great news! We're on track to hit our enrollment goal and would like to pause the incoming referrals via TrialWire."
We let the system do it's job and were very pleased with the result. Support helped quickly to get our sites logged in.

Biotech
Bay Area, USA
"Thanks again we will be back for Phase 3 and will start with TrialWire rather than bring you on for trial rescue again.”
We needed patients across 7 sites urgently and they delivered - they literally started in under 24 hours awith great support.

Biotech
San Diego, USA
"Just wanting to let you know that the referrals are flowing in and we are very excited to see all the activity.”
We wanted to get patients in quickly at startup to support our sites. They really delivered so there were no delays.
Team
Team
Team
Meet the Leadership Team
We're a team of passionate AI and Salesforce Health Cloud engineers and clinical operations specialists
FAQs
FAQs
FAQs
Frequently Asked Questions
Some of the questions clients ask us on our briefing calls
We don't want sites overwhelmed with too many non-eligable referrals - how do you manage this?
Our AI-Match screener uses study eligibility criteria to precision match people so only the most eligible get sent to the site portals.
Do you provide Platform training for sites and Sponsors and a support service?
The Platform is designed to be easy to use and very intuitive however we certainly also offer online training sessions for all team members. We also have a great support service with a 2-4 hour response rate.
Why don't you need IRB or EC submission?
So there is actually nothing to approve. Unlike the traditional adverts and micro sites we do things differently. We have a detailed document for IRB/EC as an FYI to assure everyone we are compliant.
How do we know the AI-Match screener is asking the right questions?
The questions are pulled from your own data - a protocol or clinicaltrials.gov etc. We use Perplexity, Elevenlabs and Gemini to produce some of the most advanced patient engagement tools - indeed they are consistently more accurate and accessible, with a focus on simplifying medical terms and really communicating with people so they understand what is being discussed.
Do you use databases?
We prefer to find people in real time online as they are researching their medical conditions for answers because they are motivated and high retention participants. We can get them screened and through to the sites in minutes and we find these people are more responsive to calls and texts from the sites and will attend the attend study visits.
How do you work out the per enrolled patient fee?
We use our AI Agent to review patient populations near your sites (geo-map on radius around sites) then layer this with your study criteria. Pricing is determined by patient availability, trial competition and protocol criteria.
We don't want sites overwhelmed with too many non-eligable referrals - how do you manage this?
Our AI-Match screener uses study eligibility criteria to precision match people so only the most eligible get sent to the site portals.
Do you provide Platform training for sites and Sponsors and a support service?
The Platform is designed to be easy to use and very intuitive however we certainly also offer online training sessions for all team members. We also have a great support service with a 2-4 hour response rate.
Why don't you need IRB or EC submission?
So there is actually nothing to approve. Unlike the traditional adverts and micro sites we do things differently. We have a detailed document for IRB/EC as an FYI to assure everyone we are compliant.
How do we know the AI-Match screener is asking the right questions?
The questions are pulled from your own data - a protocol or clinicaltrials.gov etc. We use Perplexity, Elevenlabs and Gemini to produce some of the most advanced patient engagement tools - indeed they are consistently more accurate and accessible, with a focus on simplifying medical terms and really communicating with people so they understand what is being discussed.
Do you use databases?
We prefer to find people in real time online as they are researching their medical conditions for answers because they are motivated and high retention participants. We can get them screened and through to the sites in minutes and we find these people are more responsive to calls and texts from the sites and will attend the attend study visits.
How do you work out the per enrolled patient fee?
We use our AI Agent to review patient populations near your sites (geo-map on radius around sites) then layer this with your study criteria. Pricing is determined by patient availability, trial competition and protocol criteria.
We don't want sites overwhelmed with too many non-eligable referrals - how do you manage this?
Our AI-Match screener uses study eligibility criteria to precision match people so only the most eligible get sent to the site portals.
Do you provide Platform training for sites and Sponsors and a support service?
The Platform is designed to be easy to use and very intuitive however we certainly also offer online training sessions for all team members. We also have a great support service with a 2-4 hour response rate.
Why don't you need IRB or EC submission?
So there is actually nothing to approve. Unlike the traditional adverts and micro sites we do things differently. We have a detailed document for IRB/EC as an FYI to assure everyone we are compliant.
How do we know the AI-Match screener is asking the right questions?
The questions are pulled from your own data - a protocol or clinicaltrials.gov etc. We use Perplexity, Elevenlabs and Gemini to produce some of the most advanced patient engagement tools - indeed they are consistently more accurate and accessible, with a focus on simplifying medical terms and really communicating with people so they understand what is being discussed.
Do you use databases?
We prefer to find people in real time online as they are researching their medical conditions for answers because they are motivated and high retention participants. We can get them screened and through to the sites in minutes and we find these people are more responsive to calls and texts from the sites and will attend the attend study visits.
How do you work out the per enrolled patient fee?
We use our AI Agent to review patient populations near your sites (geo-map on radius around sites) then layer this with your study criteria. Pricing is determined by patient availability, trial competition and protocol criteria.






















